When you save the DNG profiles you create with your ColorChecker Passport they are automatically stored in the default directory that Adobe Photoshop, Adobe Photoshop Elements and Adobe Lightroom use to store DNG profiles.
If you choose to manually manage your profiles within this folder, remember to only delete profiles if you are sure they are not being used for existing images and will not be needed in the future.
Once you have saved your profile, restart your Adobe applications to access the new DNG profile. It will be available in the Camera Calibration panel in Lightroom and Camera Raw.